SAFETY
MAVIRET AND SIDE EFFECTS
All medicines can have some unwanted side effects. Not everyone will have side effects but if you do, most of them are minor and temporary. However, some side effects may need medical attention.
The likelihood of the most common side effects are shown here.
You may not experience any of these side effects. Don’t worry – this doesn’t mean your treatment isn’t working. Most side effects are mild and don’t last long.
SIDE EFFECTS
If you are bothered by any side effects, tell your healthcare professional as soon as possible. They may be able to help you manage the side effects.
More information about side effects is available in the MAVIRET Consumer Medicine Information.
YOU MUST NOT TAKE MAVIRET:
- If you have an allergy to any medicine containing glecaprevir or pibrentasvir (the active ingredients of MAVIRET), or any non-active ingredient of MAVIRET
- If you have severe liver disease
- If you are taking atazanavir (for HIV infection) or rifampicin (for tuberculosis)
- If you are under the age of 12 years
- After the expiry date printed on the pack or if the packaging is damaged or shows signs of tampering. If it is expired or is damaged, return it to your pharmacist for disposal
TELL YOUR HEALTHCARE PROFESSIONAL IF:
- You have any allergies to any other medicines, foods, preservatives or dyes
- You have or have had any of the following medical conditions:
- liver problems other than hepatitis C
- HIV (human immunodeficiency virus)
- hepatitis B
- You have had a liver or kidney transplant
- You have diabetes
- You are pregnant or trying to become pregnant
- You are breastfeeding or are planning to breastfeed
- You have lactose intolerance
- You take any medicines for any other condition
- You have any other medical conditions
TELL YOUR HEALTHCARE PROFESSIONAL IF YOU ARE TAKING ANY OF THE FOLLOWING MEDICINES:
- Atorvastatin, lovastatin, pravastatin, rosuvastatin or simvastatin, medicines used to lower blood cholesterol
- Carbamazepine, used to treat epilepsy
- Ciclosporin, used to suppress the immune system
- Dabigatran, used to thin the blood
- Darunavir, efavirenz, lopinavir and ritonavir, used to treat HIV infection
- Digoxin, used to treat heart problems
- Ethinyloestradiol, used for contraception or hormone replacement therapy
- Fluindione, warfarin, or other similar medicines called vitamin K antagonists, used to thin the blood
- St John’s wort (Hypericum perforatum) used to treat mild depression
You should be screened for hepatitis B before starting to take MAVIRET.
This is because the hepatitis B virus can become active again during treatment with MAVIRET.
If you have any questions about MAVIRET or hep C, talk to your healthcare professional.
NZ-MAVI-180016. TAPS BG3419. October 2023.